Phenotypes associated with this allele

• Allele Symbol: Dync2i1^{Tn(pb-Act-RFP)1.1Zhu}
• Allele Name: transposon insertion 1.1, Yuan Zhuang
• Allele ID: MGI:7580876
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dync2i1^Tn(pb-Act-RFP)1.1Zhu/Dync2i1^Tn(pb-Act-RFP)1.1Zhu	involves: FVB/NJ	MGI:7608409

Genotype
MGI:7608409

hm1

• Allelic Composition: Dync2i1^{Tn(pb-Act-RFP)1.1Zhu}/Dync2i1^{Tn(pb-Act-RFP)1.1Zhu}
• Genetic Background: involves: FVB/NJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:335806 )

• die between E13.5 and E14.5

nervous system

holoprosencephaly ( J:335806 )

• at E12.5 in surviving embryos

decreased midbrain size ( J:335806 )

• at E10.5

abnormal telencephalon morphology ( J:335806 )

• smaller telencephalic evagination at E10.5

skeleton

small mandible ( J:335806 )

• at E12.5 in surviving embryos

cellular

abnormal cilium morphology ( J:335806 )

• absence of acetyl-Tubulin, a marker for cilia, in the neural tube

limbs/digits/tail

polydactyly ( J:335806 )

• at E12.5 in surviving embryos

curly tail ( J:335806 )

• twisted tail in some embryos at E10.5

homeostasis/metabolism

edema ( J:335806 )

• at E12.5 in surviving embryos

cardiac edema ( J:335806 )

• in some embryos at E10.5

craniofacial

small mandible ( J:335806 )

• at E12.5 in surviving embryos

abnormal maxillary prominence morphology ( J:335806 )

• more visible at E10.5