Phenotypes associated with this allele

• Allele Symbol: Tnrc18^em1Ggw
• Allele Name: endonuclease-mediated mutation 1, Gang Greg Wang
• Allele ID: MGI:7578774
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tnrc18^em1Ggw/Tnrc18^em1Ggw	C57BL/6-Tnrc18^em1Ggw	MGI:7578801

Genotype
MGI:7578801

hm1

• Allelic Composition: Tnrc18^em1Ggw/Tnrc18^em1Ggw
• Genetic Background: C57BL/6-Tnrc18^em1Ggw

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body size ( J:342966 )

• significantly smaller bodies of the few mice that are born, possible owing to strong endogenous retrovirus (ERV) activation in lung and liver and to a smaller extent in heart and stomach

mortality/aging

prenatal lethality, incomplete penetrance ( J:342966 )

• mice are born at below Mendelian ratio (8% homozygous from het x het mating)