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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gt(ROSA)26Sortm3(CAG-KIT*)Geno
targeted mutation 3, Genoway
MGI:7546869
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Gt(ROSA)26Sortm3(CAG-KIT*)Geno/Gt(ROSA)26Sor+
Lrig1tm1.1(cre/ERT2)Rjc/Lrig1+ 		involves: 129S6/SvEvTac * C57BL/6 MGI:8332048


Genotype
MGI:8332048
cn1
Allelic
Composition		 Gt(ROSA)26Sortm3(CAG-KIT*)Geno/Gt(ROSA)26Sor+
Lrig1tm1.1(cre/ERT2)Rjc/Lrig1+
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm3(CAG-KIT*)Geno mutation (0 available); any Gt(ROSA)26Sor mutation (1205 available)
Lrig1tm1.1(cre/ERT2)Rjc mutation (1 available); any Lrig1 mutation (51 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
increased gastrointestinal stromal tumor incidence ( J:300991 )
• adult mice given a single dose of tamoxifen exhibit small gastrointestinal stromal tumors (GIST)-like lesions in the muscularis propria of the stomach and intestine 1 month after treatment

neoplasm
increased gastrointestinal stromal tumor incidence ( J:300991 )
• adult mice given a single dose of tamoxifen exhibit small gastrointestinal stromal tumors (GIST)-like lesions in the muscularis propria of the stomach and intestine 1 month after treatment




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/05/2026
MGI 6.24 		The Jackson Laboratory