About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Skint2em2Htaka
endonuclease-mediated mutation 2, Hiroshi Takayanagi
MGI:7545259
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Skint2em2Htaka/Skint2em2Htaka C57BL/6-Skint2em2Htaka MGI:7545307


Genotype
MGI:7545307
hm1
Allelic
Composition		 Skint2em2Htaka/Skint2em2Htaka
Genetic
Background		 C57BL/6-Skint2em2Htaka
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Skint2em2Htaka mutation (0 available); any Skint2 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased dendritic epidermal T cell number ( J:291989 )
• almost complete loss of mature dendritic epidermal T cells with increases in immature CD45RBlo, CD122lo, CD24hi and CD62L+ cells

immune system
decreased dendritic epidermal T cell number ( J:291989 )
• almost complete loss of mature dendritic epidermal T cells with increases in immature CD45RBlo, CD122lo, CD24hi and CD62L+ cells

integument
decreased dendritic epidermal T cell number ( J:291989 )
• almost complete loss of mature dendritic epidermal T cells with increases in immature CD45RBlo, CD122lo, CD24hi and CD62L+ cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory