Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Elmo2tm1c(EUCOMM)Hmgu mutation
(0 available);
any
Elmo2 mutation
(37 available)
Pax3tm1(cre)Joe mutation
(1 available);
any
Pax3 mutation
(50 available)
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mortality/aging
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• fewer than expected mice are present at weaning
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Elmo1tm1.2Ravi mutation
(0 available);
any
Elmo1 mutation
(58 available)
Elmo2tm1c(EUCOMM)Hmgu mutation
(0 available);
any
Elmo2 mutation
(37 available)
Myf5tm3(cre)Sor mutation
(1 available);
any
Myf5 mutation
(17 available)
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|
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mortality/aging
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• no mice are present after weaning
• however, higher than Mendelian ratios at E14.5
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muscle
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• only mononucleated muscle cells at E14.5
• reduced muscle content at E16.5
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Elmo1tm1.2Ravi mutation
(0 available);
any
Elmo1 mutation
(58 available)
Elmo2tm1c(EUCOMM)Hmgu mutation
(0 available);
any
Elmo2 mutation
(37 available)
Pax3tm1(cre)Joe mutation
(1 available);
any
Pax3 mutation
(50 available)
|
|
|
mortality/aging
|
• no mice are present after weaning
• however, normal Mendelian ratios at E14.5
|
muscle
|
• only mononucleated muscle cells at E14.5
• reduced muscle content at E16.5
|
|
• smaller thickness at E16.5 with a failure to attach to the ribs
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Elmo2tm1c(EUCOMM)Hmgu mutation
(0 available);
any
Elmo2 mutation
(37 available)
Meox2tm1(cre)Sor mutation
(3 available);
any
Meox2 mutation
(18 available)
|
|
|
mortality/aging
|
• no mice are present at weaning
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Elmo2tm1c(EUCOMM)Hmgu mutation
(0 available);
any
Elmo2 mutation
(37 available)
Myf5tm3(cre)Sor mutation
(1 available);
any
Myf5 mutation
(17 available)
|
|
|
mortality/aging
|
• fewer than expected mice are present at weaning
|