All Phenotypes Trmt6<em1Hbgl> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Trmt6^em1Hbgl
endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI:7543517

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Tg(Cd4-cre)1Cwi/0 Trmt6^em1Hbgl/Trmt6^em1Hbgl	involves: C57BL/6 * DBA/2J	MGI:7543561

Allelic Composition	Tg(Cd4-cre)1Cwi/0 Trmt6^em1Hbgl/Trmt6^em1Hbgl
Genetic Background	involves: C57BL/6 * DBA/2J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Cd4-cre)1Cwi mutation (12 available)
Trmt6^em1Hbgl mutation (0 available); any Trmt6 mutation (29 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased T cell proliferation ( J:336736 )

• after treatment with anti-CD3and anti-CD28 antibodies

decreased CD4-positive, alpha-beta T cell number ( J:336736 )

• decreased in the spleen

hematopoietic system

decreased T cell proliferation ( J:336736 )

• after treatment with anti-CD3and anti-CD28 antibodies

decreased CD4-positive, alpha-beta T cell number ( J:336736 )

• decreased in the spleen

cellular

decreased T cell proliferation ( J:336736 )

• after treatment with anti-CD3and anti-CD28 antibodies

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24