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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Enoph1em1Zhgy
endonuclease-mediated mutation 1, Yuan Zhang
MGI:7543408
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Enoph1em1Zhgy/Enoph1em1Zhgy C57BL/6J-Enoph1em1Zhgy MGI:7543421


Genotype
MGI:7543421
hm1
Allelic
Composition		 Enoph1em1Zhgy/Enoph1em1Zhgy
Genetic
Background		 C57BL/6J-Enoph1em1Zhgy
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Enoph1em1Zhgy mutation (0 available); any Enoph1 mutation (94 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased susceptibility to ischemic brain injury ( J:336756 )
• following ischemic brain injury, mice exhibit smaller infarct size, short-term neurological deficit improvement, reduced disruption of the blood brain barrier, and diminished ischemia-induced extracellular matrix destruction compared with wild-type mice

homeostasis/metabolism
decreased susceptibility to ischemic brain injury ( J:336756 )
• following ischemic brain injury, mice exhibit smaller infarct size, short-term neurological deficit improvement, reduced disruption of the blood brain barrier, and diminished ischemia-induced extracellular matrix destruction compared with wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory