Phenotypes associated with this allele

• Allele Symbol: Arrdc5^em1Oat
• Allele Name: endonuclease-mediated mutation 1, Jon Oatley
• Allele ID: MGI:7543366
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Arrdc5^em1Oat/Arrdc5^em1Oat	involves: 129S6/SvEvTac * C57BL/6J	MGI:7543400

Genotype
MGI:7543400

hm1

• Allelic Composition: Arrdc5^em1Oat/Arrdc5^em1Oat
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reproductive system phenotype ( J:336766 )

♀N • female mice exhibit normal fertility

oligozoospermia ( J:336766 )

♂

teratozoospermia ( J:336766 )

♂ • malformed acrosomes, misshapen equatorial segments, lack of hook rims, flattened heads, and retained cytoplasm

abnormal acrosome morphology ( J:336766 )

♂

enlarged sperm head ( J:336766 )

♂ • enlarged and flattened

asthenozoospermia ( J:336766 )

♂

abnormal spermiogenesis ( J:336766 )

♂

impaired sperm capacitation ( J:336766 )

♂

male infertility ( J:336766 )

♂ • male mice fail to produce offspring

impaired acrosome reaction ( J:336766 )

♂

impaired sperm penetration of zona pellucida ( J:336766 )

♂ • with some capacity for fusion with the oocyte plasma membrane and activation when the zona pellucida is removed

cellular

oligozoospermia ( J:336766 )

♂

teratozoospermia ( J:336766 )

♂ • malformed acrosomes, misshapen equatorial segments, lack of hook rims, flattened heads, and retained cytoplasm

abnormal acrosome morphology ( J:336766 )

♂

enlarged sperm head ( J:336766 )

♂ • enlarged and flattened

asthenozoospermia ( J:336766 )

♂