Phenotypes associated with this allele

• Allele Symbol: Kif15^em1Lium
• Allele Name: endonuclease-mediated mutation 1, Mei Liu
• Allele ID: MGI:7543356
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kif15^em1Lium/Kif15^em1Lium	C57BL/6-Kif15^em1Lium	MGI:7543362

Genotype
MGI:7543362

hm1

• Allelic Composition: Kif15^em1Lium/Kif15^em1Lium
• Genetic Background: C57BL/6-Kif15^em1Lium

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

abnormal reproductive system morphology ( J:336767 )

• slight delay in testis maturity

• however, no impairment in fertility is observed

hematopoietic system

increased spleen weight ( J:336767 )

increased CD8-positive, alpha-beta T cell number ( J:336767 )

• increased percentage in the spleens of 9- and 12-week-old mice

increased spleen red pulp amount ( J:336767 )

• at 9 weeks

intermingled spleen red and white pulp ( J:336767 )

• at 9 weeks

decreased spleen white pulp amount ( J:336767 )

• at 9 weeks

neoplasm

decreased tumor growth/size ( J:336767 )

• of implanted murine melanoma B16F10 cells

growth/size/body

increased spleen weight ( J:336767 )

immune system

increased spleen weight ( J:336767 )

increased CD8-positive, alpha-beta T cell number ( J:336767 )

• increased percentage in the spleens of 9- and 12-week-old mice

increased spleen red pulp amount ( J:336767 )

• at 9 weeks

intermingled spleen red and white pulp ( J:336767 )

• at 9 weeks

decreased spleen white pulp amount ( J:336767 )

• at 9 weeks