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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Slc38a8em1Cya
endonuclease-mediated mutation 1, Cyagen Biosciences
MGI:7543297
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Slc38a8em1Cya/Slc38a8em1Cya C57BL/6J-Slc38a8em1Cya MGI:7543301


Genotype
MGI:7543301
hm1
Allelic
Composition		 Slc38a8em1Cya/Slc38a8em1Cya
Genetic
Background		 C57BL/6J-Slc38a8em1Cya
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc38a8em1Cya mutation (0 available); any Slc38a8 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
decreased susceptibility to viral infection induced morbidity/mortality ( J:336781 )
• in mice treated with foot-and-mouth disease virus and enterovirus 71

homeostasis/metabolism
decreased aspartic acid level ( J:336781 )
• in mice treated with foot-and-mouth disease virus and enterovirus 71
decreased circulating aspartate transaminase level ( J:336781 )
• in mice treated with foot-and-mouth disease virus and enterovirus 71

immune system
decreased susceptibility to viral infection ( J:336781 )
• reduced viral titer in mice treated with foot-and-mouth disease virus and enterovirus 71
decreased susceptibility to viral infection induced morbidity/mortality ( J:336781 )
• in mice treated with foot-and-mouth disease virus and enterovirus 71




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory