Phenotypes associated with this allele

• Allele Symbol: Hnrnph2^em3Jpat
• Allele Name: endonuclease-mediated mutation 3, J Paul Taylor
• Allele ID: MGI:7539578
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ot1	Hnrnph2^em3Jpat/Y	C57BL/6J-Hnrnph2^em3Jpat	MGI:7541224

Genotype
MGI:7541224

ot1

• Allelic Composition: Hnrnph2^em3Jpat/Y
• Genetic Background: C57BL/6J-Hnrnph2^em3Jpat

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

abnormal survival ( J:338313 )

♂ • males show slightly better survival rates up to 8 weeks of age compared to control males and normal long-term survival after that

craniofacial

abnormal craniofacial morphology ( J:338313 )

♂ • mice exhibit a slight, but significant, difference in the neural crest-mesoderm boundary

♂ • however, mice show no other craniofacial abnormalities

nervous system

nervous system phenotype ( J:338313 )

♂N • mice do not exhibit hydrocephalus

abnormal autonomic nervous system physiology ( J:338313 )

♂ • males exhibit decreased autonomic function scores in the SHIRPA analysis reflecting better performance in autonomic function than wild-type males

behavior/neurological

behavior/neurological phenotype ( J:338313 )

♂N • mice do not show impairments of motor function or other behaviors and no altered susceptibility to audiogenic seizures

growth/size/body

growth/size/body region phenotype ( J:338313 )

♂N • normal body weight