All Phenotypes Tent5a<em1Adki> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tent5a^em1Adki
endonuclease-mediated mutation 1, Andrzej Dziembowski
MGI:7514961

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tent5a^em1Adki/Tent5a^em1Adki	involves: C57BL/6JTar * CBA/WTar	MGI:8164369

Allelic Composition	Tent5a^em1Adki/Tent5a^em1Adki
Genetic Background	involves: C57BL/6JTar * CBA/WTar

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tent5a^em1Adki mutation (0 available); any Tent5a mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

female infertility ( J:360869 )

• complete female infertility

• however, females exhibit normal ovarian morphology and histological structure and produce a healthy pool of oocytes at the germinal vesicle stage, and germinal vesicle oocytes can mature into metaphase II oocytes in vitro

reduced male fertility ( J:360869 )

• partial male infertility

• however, morphology of sperm and testis is normal

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/18/2025 MGI 6.24