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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gpatch2em1Boui
endonuclease-mediated mutation 1, Philippe Bouillet
MGI:7514926
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gpatch2em1Boui/Gpatch2em1Boui C57BL/6-Gpatch2em1Boui MGI:7514934


Genotype
MGI:7514934
hm1
Allelic
Composition		 Gpatch2em1Boui/Gpatch2em1Boui
Genetic
Background		 C57BL/6-Gpatch2em1Boui
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gpatch2em1Boui mutation (0 available); any Gpatch2 mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:336774 )
N
• no significant difference in response to LPS, LPS-induced TNF production by macrophages, or response in the SMAC-mimetic induced skin inflammation assay
decreased B cell number ( J:336774 )
• small but significant reduction in the frequency of B cells in the blood

reproductive system
reproductive system phenotype ( J:336774 )
N
• males and females are fertile

hematopoietic system
decreased B cell number ( J:336774 )
• small but significant reduction in the frequency of B cells in the blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory