Phenotypes associated with this allele

• Allele Symbol: Foxi3^em3Akg
• Allele Name: endonuclease-mediated mutation 3, Andrew K Groves
• Allele ID: MGI:7493424
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Foxi3^em3Akg/Foxi3^em3Akg	C57BL/6-Foxi3^em3Akg	MGI:7493637
ht2	Foxi3^em3Akg/Foxi3^tm1.2Akg	involves: 129X1/SvJ * C57BL/6	MGI:7493640

Genotype
MGI:7493637

hm1

• Allelic Composition: Foxi3^em3Akg/Foxi3^em3Akg
• Genetic Background: C57BL/6-Foxi3^em3Akg

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

normal phenotype

no abnormal phenotype detected ( J:336768 )

• mice show no obvious pathological phenotypes

Genotype
MGI:7493640

ht2

• Allelic Composition: Foxi3^em3Akg/Foxi3^tm1.2Akg
• Genetic Background: involves: 129X1/SvJ * C57BL/6

mortality/aging

postnatal lethality, complete penetrance ( J:336768 )

• mice die between birth and day 5

respiratory system

abnormal respiration ( J:336768 )

• mice exhibit respiratory abnormalities

growth/size/body

decreased body weight ( J:336768 )

• mice are underweight and fail to thrive after birth

endocrine/exocrine glands

athymia ( J:336768 )

hematopoietic system

athymia ( J:336768 )

immune system

athymia ( J:336768 )

craniofacial

craniofacial phenotype ( J:336768 )

N • mice do not show defects in the mandible or the maxilla

hearing/vestibular/ear

hearing/vestibular/ear phenotype ( J:336768 )

N • mice do not show defects in the external, middle, or inner ears