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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ccser2em1Skpk
endonuclease-mediated mutation 1, Sang Ki Park
MGI:7481241
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ccser2em1Skpk/Ccser2em1Skpk C57BL/6N-Ccser2em1Skpk MGI:7481298


Genotype
MGI:7481298
hm1
Allelic
Composition		 Ccser2em1Skpk/Ccser2em1Skpk
Genetic
Background		 C57BL/6N-Ccser2em1Skpk
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccser2em1Skpk mutation (0 available); any Ccser2 mutation (58 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, incomplete penetrance ( J:333716 )
• fewer than expected mice are present at P28
• however, normal numbers of mice are present at E18.5

nervous system
abnormal neuronal migration ( J:333716 )
• with a decrease in the length without changing the orientation of the leading process
abnormal cerebral cortex morphology ( J:333716 )
• impaired cortical lamination

cellular
abnormal neuronal migration ( J:333716 )
• with a decrease in the length without changing the orientation of the leading process




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory