Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sox9tm1.1Ksec mutation
(0 available);
any
Sox9 mutation
(32 available)
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behavior/neurological
growth/size/body
reproductive system
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sox9tm1.1Ksec mutation
(0 available);
any
Sox9 mutation
(32 available)
Tg(Rr141-cre)1Ksec mutation
(0 available)
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behavior/neurological
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• impaired contact righting starting before weaning
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hearing/vestibular/ear
N |
• normal otic vesicles in E9.5embryos
• normal scala vestibuli morphology in adult mice
• normal hair cell and stereocilia arrangement in organ of Corti at age P4
• normal apoptosis rates of cochlea epithelial cells in E14.5 e
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• ~3.2x larger cross-section of basal cochlear lumen in E15.5 embryos
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• doubled in size in adult mice
• dilation of cochlear duct starting in E15 em
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• ~30% smaller in adult mice
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• in adult mice and E16.5 embryos
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• hearing deficit from 40 to 80 dB starting before weaning
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sox10tm1Ngan mutation
(0 available);
any
Sox10 mutation
(33 available)
Sox9tm1.1Ksec mutation
(0 available);
any
Sox9 mutation
(32 available)
Tg(Rr141-cre)1Ksec mutation
(0 available)
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hearing/vestibular/ear
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• ~2.7x larger cross-section of basal cochlear lumen in E15.5 embryos
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