Phenotypes associated with this allele

• Allele Symbol: Kcnt1^em1Nju
• Allele Name: endonuclease-mediated mutation 1, Model Animal Research Center of Nanjing University
• Allele ID: MGI:7449379
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kcnt1^em1Nju/Kcnt1^em1Nju	involves: C57BL/6J	MGI:7450816

Genotype
MGI:7450816

hm1

• Allelic Composition: Kcnt1^em1Nju/Kcnt1^em1Nju
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:333464 )

N • normal total distance traveled in elevated plus maze (EPM) and travel velocity in open field test (OFT)

decreased thigmotaxis ( J:333464 )

• in open field test (OFT) and elevated plus maze (EPM)

nervous system

nervous system phenotype ( J:333464 )

• normal slow afterhyperpolarization in basolateral amygdala glutamatergic neurons

abnormal nervous system electrophysiology ( J:333464 )

• lower resting potential in basolateral amygdala excitatory neurons

impaired ability to fire action potentials ( J:333464 )

• fewer action potentials in response to depolarization current in basolateral amygdala glutamatergic neurons