About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Lgi2tm1.2Mejr
targeted mutation 1.2, Dies Meijer
MGI:7444283
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Lgi2tm1.2Mejr/Lgi2tm1.2Mejr Not Specified MGI:7444414
cx2
 		Lgi2tm1.2Mejr/Lgi2tm1.2Mejr
Lgi3tm1.2Mejr/Lgi3tm1.2Mejr 		Not Specified MGI:7444417


Genotype
MGI:7444414
hm1
Allelic
Composition		 Lgi2tm1.2Mejr/Lgi2tm1.2Mejr
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lgi2tm1.2Mejr mutation (0 available); any Lgi2 mutation (28 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:333962 )
• mice develop normally with normal lifespans and fertility




Genotype
MGI:7444417
cx2
Allelic
Composition		 Lgi2tm1.2Mejr/Lgi2tm1.2Mejr
Lgi3tm1.2Mejr/Lgi3tm1.2Mejr
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lgi2tm1.2Mejr mutation (0 available); any Lgi2 mutation (28 available)
Lgi3tm1.2Mejr mutation (0 available); any Lgi3 mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

nervous system
abnormal neuron morphology ( J:333962 )
• absent Kv1 channels complex accumulation at the juxtaparanodal membrane in neurons

growth/size/body
postnatal growth retardation ( J:333962 )

behavior/neurological
tremors ( J:333962 )
• from the second postnatal week




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory