Phenotypes associated with this allele

• Allele Symbol: Rr273^em1Issa
• Allele Name: endonuclease-mediated mutation 1, Issam Aldiri
• Allele ID: MGI:7443203
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rr273^em1Issa/Rr273^em1Issa	involves: C57BL/6J * DBA/2J	MGI:7444212

Genotype
MGI:7444212

hm1

• Allelic Composition: Rr273^em1Issa/Rr273^em1Issa
• Genetic Background: involves: C57BL/6J * DBA/2J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

vision/eye phenotype ( J:333875 )

N • all retinal layers and cell types are present, but reduced in size/number

retina pigment epithelium hyperplasia ( J:333875 )

• excessive pigmented cells in retinal periphery in E14.5 embryos and P0 mice

microphthalmia ( J:333875 )

• small eyes in E14.5 embryos and P22 mice

pigmentation

retina pigment epithelium hyperplasia ( J:333875 )

• excessive pigmented cells in retinal periphery in E14.5 embryos and P0 mice

cellular

decreased cell proliferation ( J:333875 )

• decreased retinal cell proliferation in embryos