All Phenotypes Rr381<em5Kap> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Rr381^em5Kap
endonuclease-mediated mutation 5, Dietmar J Kappes
MGI:7439139

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rr381^em5Kap/Rr381^em5Kap	involves: C57BL/6	MGI:7439205
cx2	H2^dlAb1-Ea/H2^dlAb1-Ea Rr381^em5Kap/Rr381^em5Kap	involves: 129S2/SvPas * C57BL/6	MGI:7439206

Allelic Composition	Rr381^em5Kap/Rr381^em5Kap
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

absent CD8-positive, alpha-beta T cells ( J:333471 )

immune system

absent CD8-positive, alpha-beta T cells ( J:333471 )

Allelic Composition	H2^dlAb1-Ea/H2^dlAb1-Ea Rr381^em5Kap/Rr381^em5Kap
Genetic Background	involves: 129S2/SvPas * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2^dlAb1-Ea mutation (13 available); any H2 mutation (280 available)
Rr381^em5Kap mutation (0 available); any Rr381 mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

absent CD8-positive, alpha-beta T cells ( J:333471 )

• almost complete redirection of MHC class I-specific T cells to CD4+ lineage

immune system

absent CD8-positive, alpha-beta T cells ( J:333471 )

• almost complete redirection of MHC class I-specific T cells to CD4+ lineage

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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