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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rr381em1Kap
endonuclease-mediated mutation 1, Dietmar J Kappes
MGI:7439129
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rr381em1Kap/Rr381em1Kap involves: C57BL/6 MGI:7439196


Genotype
MGI:7439196
hm1
Allelic
Composition		 Rr381em1Kap/Rr381em1Kap
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
absent CD8-positive, alpha-beta T cells ( J:333471 )
• extremely high single-positive CD4+ to CD8+ T cell ratio owing to virtual absence of latter

immune system
absent CD8-positive, alpha-beta T cells ( J:333471 )
• extremely high single-positive CD4+ to CD8+ T cell ratio owing to virtual absence of latter




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory