All Phenotypes Cdh2<em2Obir> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Cdh2^em2Obir
endonuclease-mediated mutation 2, Ohad S Birk
MGI:7432736

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cdh2^em2Obir/Cdh2^em2Obir	C57BL/6JRcc-Cdh2^em2Obir	MGI:7434354

Allelic Composition	Cdh2^em2Obir/Cdh2^em2Obir
Genetic Background	C57BL/6JRcc-Cdh2^em2Obir

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdh2^em2Obir mutation (0 available); any Cdh2 mutation (50 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

hyperactivity ( J:331911 )

• 12-week-old males mice exhibit a greater traveling distance, increased velocity, prolonged mobility time, and an increase in the number of center zone alternation in the open field test

• acute methylphenidate intervention aggravates locomotor activity

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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