Phenotypes associated with this allele

• Allele Symbol: Heph^{em1(IMPC)Ccpcz}
• Allele Name: endonuclease-mediated mutation 1, Institute of Molecular Genetics
• Allele ID: MGI:7425739
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Heph^em1(IMPC)Ccpcz/Heph^em1(IMPC)Ccpcz	C57BL/6NCrl-Heph^em1(IMPC)Ccpcz/Ccpcz	MGI:7472040
ot2	Heph^em1(IMPC)Ccpcz/Y	C57BL/6NCrl-Heph^em1(IMPC)Ccpcz/Ccpcz	MGI:7472039

Genotype
MGI:7472040

hm1

• Allelic Composition: Heph^{em1(IMPC)Ccpcz}/Heph^{em1(IMPC)Ccpcz}
• Genetic Background: C57BL/6NCrl-Heph^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Heph

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased circulating iron level ( J:211773 )

♀

IMPC - CCP-IMG

increased circulating phosphate level ( J:211773 )

♀

IMPC - CCP-IMG

increased circulating alanine transaminase level ( J:211773 )

♀

IMPC - CCP-IMG

increased circulating aspartate transaminase level ( J:211773 )

♀

IMPC - CCP-IMG

immune system

abnormal lymph node morphology ( J:211773 )

♀

IMPC - CCP-IMG

enlarged lymph nodes ( J:211773 )

♀

IMPC - CCP-IMG

Genotype
MGI:7472039

ot2

• Allelic Composition: Heph^{em1(IMPC)Ccpcz}/Y
• Genetic Background: C57BL/6NCrl-Heph^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Heph

cardiovascular system

abnormal heart morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

homeostasis/metabolism

increased circulating iron level ( J:211773 )

♂

IMPC - CCP-IMG

increased circulating creatine kinase level ( J:211773 )

♂

IMPC - CCP-IMG

immune system

abnormal lymph node morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged lymph nodes ( J:211773 )

♂

IMPC - CCP-IMG