Phenotypes associated with this allele

• Allele Symbol: Fras1^{em1(IMPC)Ccpcz}
• Allele Name: endonuclease-mediated mutation 1, Institute of Molecular Genetics
• Allele ID: MGI:7425689
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fras1^em1(IMPC)Ccpcz/Fras1^em1(IMPC)Ccpcz	C57BL/6NCrl-Fras1^em1(IMPC)Ccpcz/Ph	MGI:7768338
ht2	Fras1^em1(IMPC)Ccpcz/Fras1^+	C57BL/6NCrl-Fras1^em1(IMPC)Ccpcz/Ph	MGI:7768337

Genotype
MGI:7768338

hm1

• Allelic Composition: Fras1^{em1(IMPC)Ccpcz}/Fras1^{em1(IMPC)Ccpcz}
• Genetic Background: C57BL/6NCrl-Fras1^{em1(IMPC)Ccpcz}/Ph

Data Sources

IMPC Data for Fras1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal facial morphology ( J:211773 )

IMPC - CCP-IMG

abnormal head shape ( J:211773 )

IMPC - CCP-IMG

embryo

embryonic growth retardation ( J:211773 )

IMPC - CCP-IMG

abnormal embryo size ( J:211773 )

IMPC - CCP-IMG

growth/size/body

abnormal facial morphology ( J:211773 )

IMPC - CCP-IMG

abnormal head shape ( J:211773 )

IMPC - CCP-IMG

embryonic growth retardation ( J:211773 )

IMPC - CCP-IMG

abnormal embryo size ( J:211773 )

IMPC - CCP-IMG

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - CCP-IMG

vision/eye

abnormal eyelid fusion ( J:211773 )

IMPC - CCP-IMG

Genotype
MGI:7768337

ht2

• Allelic Composition: Fras1^{em1(IMPC)Ccpcz}/Fras1⁺
• Genetic Background: C57BL/6NCrl-Fras1^{em1(IMPC)Ccpcz}/Ph

Data Sources

IMPC Data for Fras1

hematopoietic system

increased mean corpuscular hemoglobin concentration ( J:211773 )

♂

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

IMPC - CCP-IMG

immune system

abnormal spleen morphology ( J:211773 )

IMPC - CCP-IMG

respiratory system

increased airway resistance ( J:211773 )

♂

IMPC - CCP-IMG

skeleton

abnormal vertebrae morphology ( J:211773 )

♀

IMPC - CCP-IMG