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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Creb3l2em1(IMPC)Ccpcz
endonuclease-mediated mutation 1, Institute of Molecular Genetics
MGI:7425607
Summary 2 genotypes


Genotype
MGI:8176163
hm1
Allelic
Composition		 Creb3l2em1(IMPC)Ccpcz/Creb3l2em1(IMPC)Ccpcz
Genetic
Background		 C57BL/6NCrl-Creb3l2em1(IMPC)Ccpcz/Ccpcz
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Creb3l2em1(IMPC)Ccpcz mutation (1 available); any Creb3l2 mutation (22 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
cleft palate ( J:211773 )
IMPC - CCP-IMG
protruding tongue ( J:211773 )
IMPC - CCP-IMG
abnormal head shape ( J:211773 )
IMPC - CCP-IMG

digestive/alimentary system
cleft palate ( J:211773 )
IMPC - CCP-IMG
protruding tongue ( J:211773 )
IMPC - CCP-IMG

embryo
abnormal embryo size ( J:211773 )
IMPC - CCP-IMG

growth/size/body
cleft palate ( J:211773 )
IMPC - CCP-IMG
protruding tongue ( J:211773 )
IMPC - CCP-IMG
abnormal head shape ( J:211773 )
IMPC - CCP-IMG
abnormal embryo size ( J:211773 )
IMPC - CCP-IMG
abnormal head size ( J:211773 )
IMPC - CCP-IMG

homeostasis/metabolism
edema ( J:211773 )
IMPC - CCP-IMG

limbs/digits/tail

mortality/aging




Genotype
MGI:7768312
ht2
Allelic
Composition		 Creb3l2em1(IMPC)Ccpcz/Creb3l2+
Genetic
Background		 C57BL/6NCrl-Creb3l2em1(IMPC)Ccpcz/Ccpcz
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Creb3l2em1(IMPC)Ccpcz mutation (1 available); any Creb3l2 mutation (22 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
enlarged spleen ( J:211773 )
IMPC - CCP-IMG

hematopoietic system
enlarged spleen ( J:211773 )
IMPC - CCP-IMG

immune system
enlarged spleen ( J:211773 )
IMPC - CCP-IMG

integument

vision/eye
cataract ( J:211773 )
IMPC - CCP-IMG




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory