Phenotypes associated with this allele

• Allele Symbol: Cd27^{em1(IMPC)Ccpcz}
• Allele Name: endonuclease-mediated mutation 1, Institute of Molecular Genetics
• Allele ID: MGI:7425569
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cd27^em1(IMPC)Ccpcz/Cd27^em1(IMPC)Ccpcz	C57BL/6NCrl-Cd27^em1(IMPC)Ccpcz/Ccpcz	MGI:7471926

Genotype
MGI:7471926

hm1

• Allelic Composition: Cd27^{em1(IMPC)Ccpcz}/Cd27^{em1(IMPC)Ccpcz}
• Genetic Background: C57BL/6NCrl-Cd27^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Cd27

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal heart morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

endocrine/exocrine glands

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - CCP-IMG

small seminal vesicle ( J:211773 )

♂

IMPC - CCP-IMG

abnormal testis morphology ( J:211773 )

♂

IMPC - CCP-IMG

small testis ( J:211773 )

♂

IMPC - CCP-IMG

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

decreased lean body mass ( J:211773 )

♂

IMPC - CCP-IMG

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - CCP-IMG

hematopoietic system

decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number ( J:211773 )

♂

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

♀

IMPC - CCP-IMG

immune system

decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number ( J:211773 )

♂

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

♀

IMPC - CCP-IMG

nervous system

increased prepulse inhibition ( J:211773 )

IMPC - CCP-IMG

reproductive system

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - CCP-IMG

small seminal vesicle ( J:211773 )

♂

IMPC - CCP-IMG

abnormal testis morphology ( J:211773 )

♂

IMPC - CCP-IMG

small testis ( J:211773 )

♂

IMPC - CCP-IMG