Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wapltm1.2Kpfe mutation
(0 available);
any
Wapl mutation
(168 available)
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mortality/aging
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• not recoverable at the blastocyst stage
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|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wapltm1.1Kpfe mutation
(1 available);
any
Wapl mutation
(168 available)
Wapltm1.2Kpfe mutation
(0 available);
any
Wapl mutation
(168 available)
|
|
|
mortality/aging
|
• found in expected numbers at E17.5 but absent at weaning
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
NipblGt(EUCE313f02)1.2Hmgu mutation
(0 available);
any
Nipbl mutation
(124 available)
Wapltm1.2Kpfe mutation
(0 available);
any
Wapl mutation
(168 available)
|
|
|
embryo
|
• embryos are significantly larger than mutant mice wild-type for Wapl
• partial rescue of about 24% of reduced embryo growth phenotype
|
mortality/aging
growth/size/body
|
• embryos are significantly larger than mutant mice wild-type for Wapl
• partial rescue of about 24% of reduced embryo growth phenotype
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
NipblGt(EUCE313f02)1.2Hmgu mutation
(0 available);
any
Nipbl mutation
(124 available)
Wapltm1.1Kpfe mutation
(1 available);
any
Wapl mutation
(168 available)
Wapltm1.2Kpfe mutation
(0 available);
any
Wapl mutation
(168 available)
|
|
|
embryo
|
• embryos are significantly larger than mutant mice wild-type for Wapl
• partial rescue of about 24% of reduced embryo growth phenotype
|
mortality/aging
growth/size/body
|
• embryos are significantly larger than mutant mice wild-type for Wapl
• partial rescue of about 24% of reduced embryo growth phenotype
|