Phenotypes associated with this allele

• Allele Symbol: Uqcc6^em1Lenh
• Allele Name: endonuclease-mediated mutation 1, Lena Ho
• Allele ID: MGI:7413183
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Uqcc6^em1Lenh/Uqcc6^em1Lenh	C57BL/6J-Uqcc6^em1Lenh	MGI:7413188

Genotype
MGI:7413188

hm1

• Allelic Composition: Uqcc6^em1Lenh/Uqcc6^em1Lenh
• Genetic Background: C57BL/6J-Uqcc6^em1Lenh

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased circulating lactate level ( J:330815 )

• mild

abnormal response to exercise ( J:330815 )

• reduced exercise tolerance

cellular

abnormal respiratory electron transport chain ( J:330815 )

• mice exhibit depletion of CII in the mitochondrial