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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rn7sktm1.1Mfrye
targeted mutation 1.1, Michaela Frye
MGI:7386917
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+
Rn7sktm1.1Mfrye/Rn7sktm1.1Mfrye
Tg(KRT14-cre/ERT)20Efu/0 		involves: 129 * C57BL/6NCrl * CBA * CD-1 * SJL MGI:7386922


Genotype
MGI:7386922
cn1
Allelic
Composition		 Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+
Rn7sktm1.1Mfrye/Rn7sktm1.1Mfrye
Tg(KRT14-cre/ERT)20Efu/0
Genetic
Background		 involves: 129 * C57BL/6NCrl * CBA * CD-1 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm9(CAG-tdTomato)Hze mutation (4 available); any Gt(ROSA)26Sor mutation (944 available)
Rn7sktm1.1Mfrye mutation (0 available); any Rn7sk mutation (2 available)
Tg(KRT14-cre/ERT)20Efu mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
abnormal epidermal layer morphology ( J:331226 )
• reduced cellularity in tamoxifen-treated mice from P4
• however, mice recover one month after the last tamoxifen application




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory