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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rr293tm1.1Mekk
targeted mutation 1.1, Marc Ekker
MGI:7356588
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rr293tm1.1Mekk/Rr293tm1.1Mekk involves: 129S/SvEv * C57BL/6N MGI:7356616
cx2
 		Rr291tm1.1Mekk/Rr291tm1.1Mekk
Rr293tm1.1Mekk/Rr293tm1.1Mekk 		involves: 129S/SvEv * C57BL/6N MGI:7356618
cx3
 		Rr291tm2.1Mekk/Rr291tm2.1Mekk
Rr293tm1.1Mekk/Rr293tm1.1Mekk 		Not Specified MGI:7356619


Genotype
MGI:7356616
hm1
Allelic
Composition		 Rr293tm1.1Mekk/Rr293tm1.1Mekk
Genetic
Background		 involves: 129S/SvEv * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
embryo phenotype ( J:312374 )
• no obvious developmental phenotype

mortality/aging
mortality/aging ( J:312374 )
• viable

reproductive system




Genotype
MGI:7356618
cx2
Allelic
Composition		 Rr291tm1.1Mekk/Rr291tm1.1Mekk
Rr293tm1.1Mekk/Rr293tm1.1Mekk
Genetic
Background		 involves: 129S/SvEv * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:312374 )
N
• normal behavior in beam brake, elevated plus maze and open field tests
increased social investigation ( J:312374 )
• increased interaction with juvenile




Genotype
MGI:7356619
cx3
Allelic
Composition		 Rr291tm2.1Mekk/Rr291tm2.1Mekk
Rr293tm1.1Mekk/Rr293tm1.1Mekk
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:312374 )
N
• normal behavior in beam brake, elevated plus maze and open field tests




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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory