About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rr266em1Hino
endonuclease-mediated mutation 1, Hirofumi Noguchi
MGI:7338992
Summary 2 genotypes


Genotype
MGI:7339113
hm1
Allelic
Composition		 Rr266em1Hino/Rr266em1Hino
Genetic
Background		 C57BL/6J-Rr266em1Hino
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
homeostasis/metabolism phenotype ( J:312429 )
N
• no diabetes or hyperglycemia; normal glucose tolerance and insulin levels




Genotype
MGI:7339120
cx2
Allelic
Composition		 Rr266em1Hino/Rr266em1Hino
Rr268em1Hino/Rr268em1Hino
Genetic
Background		 C57BL/6J-Rr266em1Hino Rr268em1Hino
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands

growth/size/body
decreased body weight ( J:312429 )
• at ages 6 and 12 weeks

homeostasis/metabolism
hyperglycemia ( J:312429 )
• increased blood glucose levels after feeding and after fasting at ages 6 and 12 weeks
impaired glucose tolerance ( J:312429 )
• increased blood glucose levels after glucose administration

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
diabetes mellitus DOID:9351 J:312429




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory