Phenotypes associated with this allele

• Allele Symbol: Del(2Rr263-Rr264)1Maros
• Allele Name: deletion, Chr 2, Marian A Ros
• Allele ID: MGI:7335223
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Del(2Rr263-Rr264)1Maros/Del(2Rr263-Rr264)1Maros	involves: C57BL/6 * CBA	MGI:7336017

Genotype
MGI:7336017

hm1

• Allelic Composition: Del(2Rr263-Rr264)1Maros/Del(2Rr263-Rr264)1Maros
• Genetic Background: involves: C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal locomotor behavior ( J:312494 )

• mice cannot walk; mice use undulating or wriggling motion

embryo

embryo phenotype ( J:312494 )

N • viable

integument

absence of all nails ( J:312494 )

limbs/digits/tail

abnormal autopod morphology ( J:312494 )

• dorsal hair absent from autopods

• biventral distal limb elements with dorsoventral symmetrical distal phalanges and talus bones

abnormal foot pad morphology ( J:312494 )

• foot pads present on dorsal side of autopods (in addition to ventral)

abnormal limb bone morphology ( J:312494 )

• biventral distal limb elements with dorsoventral symmetrical distal phalanges, talus bones and sesamoid bones

abnormal phalanx morphology ( J:312494 )

• loss of dorsalization during embryonic development: biventral distal limb elements with dorsoventral symmetrical (duplicated) distal phalanges

abnormal talus morphology ( J:312494 )

• loss of dorsalization during embryonic development: biventral distal limb elements with dorsoventral symmetrical talus bones

absent patella ( J:312494 )

abnormal sesamoid bone of gastrocnemius morphology ( J:312494 )

• loss of dorsalization during embryonic development: biventral distal skeletal elements with dorsoventral symmetrical (duplicated) sesamoid bones

abnormal limb development ( J:312494 )

• loss of dorsalization during embryonic development: biventral distal limb elements with dorsoventral symmetrical distal phalanges, talus bones and sesamoid bones

• absent patella

nervous system

nervous system phenotype ( J:312494 )

N • normal cerebellum morphology

renal/urinary system

renal/urinary system phenotype ( J:312494 )

N • normal kidney morphology

skeleton

abnormal limb bone morphology ( J:312494 )

• biventral distal limb elements with dorsoventral symmetrical distal phalanges, talus bones and sesamoid bones

abnormal phalanx morphology ( J:312494 )

• loss of dorsalization during embryonic development: biventral distal limb elements with dorsoventral symmetrical (duplicated) distal phalanges

abnormal talus morphology ( J:312494 )

• loss of dorsalization during embryonic development: biventral distal limb elements with dorsoventral symmetrical talus bones

absent patella ( J:312494 )

abnormal sesamoid bone of gastrocnemius morphology ( J:312494 )

• loss of dorsalization during embryonic development: biventral distal skeletal elements with dorsoventral symmetrical (duplicated) sesamoid bones

vision/eye

vision/eye phenotype ( J:312494 )

N • normal eye morphology