Phenotypes associated with this allele

• Allele Symbol: Mettl15^em1Pvs
• Allele Name: endonuclease-mediated mutation 1, Petr V Sergiev
• Allele ID: MGI:7335017
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mettl15^em1Pvs/Mettl15^em1Pvs	involves: C57BL/6 * CBA	MGI:7335029

Genotype
MGI:7335029

hm1

• Allelic Composition: Mettl15^em1Pvs/Mettl15^em1Pvs
• Genetic Background: involves: C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

impaired learning ( J:325995 )

• mice exhibit impaired learning test in a light-dark box with electric foot shock and the box maze test compared with wild-type mice

decreased thermal nociceptive threshold ( J:325995 )

• increased sensitivity on a hot plate

homeostasis/metabolism

hypoglycemia ( J:325995 )

• after physical exercise

cellular

increased mitochondrial DNA content ( J:325995 )

• in the liver and cardiac muscle

early cellular replicative senescence ( J:325995 )

• nearly 2-fold increase in kidney cells