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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gm34583tm1.1Bcgen
targeted mutation 1.1, Biocytogen LLC
MGI:7334829
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Gm34583tm1.1Bcgen/Gm34583tm1.1Bcgen B6(Cg)-Gm34583tm1.1Bcgen MGI:7334894
cn2
 		Gm34583tm1.1Bcgen/Gm34583tm1.1Bcgen
Aviltm2(cre)Fawa/Avil+ 		involves: 129P2/OlaHsd * C57BL/6 MGI:7334895


Genotype
MGI:7334894
cn1
Allelic
Composition		 Gm34583tm1.1Bcgen/Gm34583tm1.1Bcgen
Genetic
Background		 B6(Cg)-Gm34583tm1.1Bcgen
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
hypoalgesia ( J:326871 )
• following chronic constriction injury, mice injected with an adenovirus expressing cre exhibit mitigated nerve injury-induced mechanical, heat, and cold nociceptive hypersensitivities with reduced paw withdrawal percentage compared with control mice

homeostasis/metabolism
decreased susceptibility to injury ( J:326871 )
• following chronic constriction injury, mice injected with an adenovirus expressing cre exhibit mitigated nerve injury-induced mechanical, heat, and cold nociceptive hypersensitivities with reduced paw withdrawal percentage and reduced L4 spinal nerve ligation-induced dorsal horn neuronal/glial hyperactivities compared with control mice




Genotype
MGI:7334895
cn2
Allelic
Composition		 Gm34583tm1.1Bcgen/Gm34583tm1.1Bcgen
Aviltm2(cre)Fawa/Avil+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aviltm2(cre)Fawa mutation (2 available); any Avil mutation (46 available)
Gm34583tm1.1Bcgen mutation (0 available); any Gm34583 mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
hypoalgesia ( J:326871 )
• following L4 spinal nerve ligation-induced, mice exhibit mitigated nerve injury-induced mechanical, heat, and cold nociceptive hypersensitivities with reduced paw withdrawal percentage compared with control mice

homeostasis/metabolism
decreased susceptibility to injury ( J:326871 )
• following L4 spinal nerve ligation-induced, mice exhibit mitigated nerve injury-induced mechanical, heat, and cold nociceptive hypersensitivities with reduced paw withdrawal percentage compared with control mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory