All Phenotypes Usp45<em1Qzha> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Usp45^em1Qzha
endonuclease-mediated mutation 1, Qingjiong Zhang
MGI:7329914

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Usp45^em1Qzha/Usp45^em1Qzha	C57BL/6J-Usp45^em1Qzha	MGI:7329919

Allelic Composition	Usp45^em1Qzha/Usp45^em1Qzha
Genetic Background	C57BL/6J-Usp45^em1Qzha

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Usp45^em1Qzha mutation (0 available); any Usp45 mutation (50 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

decreased retina cone cell number ( J:282594 )

• mice exhibit fewer cones by 20 weeks of age

abnormal cone electrophysiology ( J:282594 )

• mice show severely reduced photopic response

abnormal rod electrophysiology ( J:282594 )

• mice show severely reduced scotopic response

nervous system

decreased retina cone cell number ( J:282594 )

• mice exhibit fewer cones by 20 weeks of age

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Leber congenital amaurosis 19		DOID:0081169	OMIM:618513	J:282594

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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