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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Trim6em1Raj
endonuclease-mediated mutation 1, Ricardo Rajsbaum
MGI:7327325
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Trim6em1Raj/Trim6em1Raj C57BL/6J-Trim6em1Raj MGI:7327335


Genotype
MGI:7327335
hm1
Allelic
Composition		 Trim6em1Raj/Trim6em1Raj
Genetic
Background		 C57BL/6J-Trim6em1Raj
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trim6em1Raj mutation (0 available); any Trim6 mutation (55 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal response to infection ( J:326927 )
• primary bone marrow-derived dendritic cells (BMDCs) infected with recombinant Ebola virus show lower viral genomic RNA copy number and lower Ebola virus titer than in wild-type cells and primary MEFs infected with recombinant Ebola virus exhibit lower viral RNA copy number indicating that viral replication is attenuated




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/21/2024
MGI 6.23 		The Jackson Laboratory