Phenotypes associated with this allele

• Allele Symbol: Ptgs2os^tm1Scrp
• Allele Name: targeted mutation 1, Susan Carpenter
• Allele ID: MGI:7314907
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ptgs2os^tm1Scrp/Ptgs2os^tm1Scrp	Not Specified	MGI:7314910

Genotype
MGI:7314910

hm1

• Allelic Composition: Ptgs2os^tm1Scrp/Ptgs2os^tm1Scrp
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

decreased neutrophil cell number ( J:325487 )

• in the bronchoalveolar fluid of LPS-treated mice

decreased circulating interleukin-6 level ( J:325487 )

• of LPS-treated mice

abnormal chemokine level ( J:325487 )

• LPS-treated mice exhibit reduced serum and BAL levels of Ccl4, increased serum levels of Ccl5 and Ccl22 compared with wild-type mice

decreased CCL3 level ( J:325487 )

• in the bronchoalveolar fluid of LPS-treated mice

decreased circulating CCL3 level ( J:325487 )

• of LPS-treated mice

increased interferon-beta secretion ( J:325487 )

• in the bronchoalveolar fluid of LPS-treated mice

homeostasis/metabolism

decreased circulating interleukin-6 level ( J:325487 )

• of LPS-treated mice

abnormal chemokine level ( J:325487 )

• LPS-treated mice exhibit reduced serum and BAL levels of Ccl4, increased serum levels of Ccl5 and Ccl22 compared with wild-type mice

decreased CCL3 level ( J:325487 )

• in the bronchoalveolar fluid of LPS-treated mice

decreased circulating CCL3 level ( J:325487 )

• of LPS-treated mice

hematopoietic system

decreased neutrophil cell number ( J:325487 )

• in the bronchoalveolar fluid of LPS-treated mice