Phenotypes associated with this allele

• Allele Symbol: Zng1^em2Skan
• Allele Name: endonuclease-mediated mutation 2, Shoichiro Konda
• Allele ID: MGI:7309151
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Zng1^em2Skan/Zng1^em2Skan	C57BL/6N-Zng1^em2Skan	MGI:7309156

Genotype
MGI:7309156

hm1

• Allelic Composition: Zng1^em2Skan/Zng1^em2Skan
• Genetic Background: C57BL/6N-Zng1^em2Skan

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

renal/urinary system

abnormal renal/urinary system morphology ( J:326010 )

• 60% of mice exhibit identifiable congenital anomalies of the kidney and urinary tract (CAKUT) phenotypes

abnormal kidney interstitium morphology ( J:326010 )

• hyperplasia of the renal interstitium is seen in the kidney

hydronephrosis ( J:326010 )

• pups show hydronephrosis

abnormal renal tubule morphology ( J:326010 )

• construction of rental tubules is disrupted

double ureter ( J:326010 )

• duplicated ureters in 4-week-old mice

hydroureter ( J:326010 )

• pups show hydroureter

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
CAKUT		DOID:0080205	OMIM:PS610805	J:326010