All Phenotypes Trex1<em1Gpt> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Trex1^em1Gpt
endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
MGI:7307837

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Arih1^em3Gpt/Arih1^em3Gpt Lyz2^em1(icre)Gpt/Lyz2⁺ Trex1^em1Gpt/Trex1^em1Gpt	C57BL/6JGpt-Arih1^em3Gpt Trex1^em1Gpt Lyz2^em1(icre)Gpt	MGI:7410894

Allelic Composition	Arih1^em3Gpt/Arih1^em3Gpt Lyz2^em1(icre)Gpt/Lyz2⁺ Trex1^em1Gpt/Trex1^em1Gpt
Genetic Background	C57BL/6JGpt-Arih1^em3Gpt Trex1^em1Gpt Lyz2^em1(icre)Gpt

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arih1^em3Gpt mutation (0 available); any Arih1 mutation (32 available)
Lyz2^em1(icre)Gpt mutation (0 available); any Lyz2 mutation (41 available)
Trex1^em1Gpt mutation (0 available); any Trex1 mutation (22 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

mortality/aging ( J:330879 )

N	• unlike Trex1^em1Gpt homozygotes, mice exhibit normal survival

immune system

immune system phenotype ( J:330879 )

N	• unlike Trex1^em1Gpt homozygotes, mice exhibit normalized spleen size and weight; serum levels of TNF, CXCL1, CCL5, and total IgG; and autoimmune phenotypes

growth/size/body

growth/size/body region phenotype ( J:330879 )

N	• unlike Trex1^em1Gpt homozygotes, mice exhibit normalized development and body weight

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