All Phenotypes Cyth2<tm1d(EUCOMM)Wtsi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Cyth2^{tm1d(EUCOMM)Wtsi}
targeted mutation 1d, Wellcome Trust Sanger Institute
MGI:7266327

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cyth2^{tm1d(EUCOMM)Wtsi}/Cyth2^{tm1d(EUCOMM)Wtsi}	involves: C57BL/6N	MGI:7310431

Allelic Composition	Cyth2^{tm1d(EUCOMM)Wtsi}/Cyth2^{tm1d(EUCOMM)Wtsi}
Genetic Background	involves: C57BL/6N
Cell Lines	EPD0140_3_D11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cyth2^{tm1d(EUCOMM)Wtsi} mutation (0 available); any Cyth2 mutation (20 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased eosinophil cell number ( J:307633 )

• reduced septal eosinophil infiltration in a model of ovalbumin-induced murine rhinitis

decreased susceptibility to type I hypersensitivity reaction ( J:307633 )

• reduced septal eosinophil infiltration in a model of ovalbumin-induced murine rhinitis

• however, goblet cell proliferation is normal

hematopoietic system

decreased eosinophil cell number ( J:307633 )

• reduced septal eosinophil infiltration in a model of ovalbumin-induced murine rhinitis

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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