Phenotypes associated with this allele

• Allele Symbol: Tg(Krt14-Ifnk)#Cya
• Allele Name: transgene insertion, Cyagen Biosciences
• Allele ID: MGI:7258010
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Krt14-Ifnk)#Cya/0	C57BL/6N-Tg(Krt14-Ifnk)#Cya	MGI:7258015

Genotype
MGI:7258015

tg1

• Allelic Composition: Tg(Krt14-Ifnk)#Cya/0
• Genetic Background: C57BL/6N-Tg(Krt14-Ifnk)#Cya

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

integument

increased susceptibility to chemically induced skin inflammation ( J:322130 )

• increased ear thickness, splenomegaly, and inflammatory score with increased macrophage, dendritic cell, and CD4+ and cD8+ T cell recruitment to the skin following IMQ treatment to induce psoriasis

immune system

enlarged spleen ( J:322130 )

• following IMQ treatment to induce psoriasis to a greater extent than in wild-type mice

increased susceptibility to chemically induced skin inflammation ( J:322130 )

• increased ear thickness, splenomegaly, and inflammatory score with increased macrophage, dendritic cell, and CD4+ and cD8+ T cell recruitment to the skin following IMQ treatment to induce psoriasis

growth/size/body

enlarged spleen ( J:322130 )

• following IMQ treatment to induce psoriasis to a greater extent than in wild-type mice

hematopoietic system

enlarged spleen ( J:322130 )

• following IMQ treatment to induce psoriasis to a greater extent than in wild-type mice