About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gpx4tm5Marc
targeted mutation 5, Marcus Conrad
MGI:6874619
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Gpx4tm5Marc/Gpx4+
Sepsecstm1.1Usch/Sepsecstm1.1Usch 		involves: 129S6/SvEvTac * C57BL/6J MGI:7367143


Genotype
MGI:7367143
cx1
Allelic
Composition		 Gpx4tm5Marc/Gpx4+
Sepsecstm1.1Usch/Sepsecstm1.1Usch
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gpx4tm5Marc mutation (0 available); any Gpx4 mutation (80 available)
Sepsecstm1.1Usch mutation (0 available); any Sepsecs mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:315052 )
N
• mice exhibit normal survival

cardiovascular system
decreased heart rate ( J:315052 )
• slightly decreased

respiratory system
respiratory system phenotype ( J:315052 )
N
• mice exhibit normal breathing frequency




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory