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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ermntm1Bcgen
targeted mutation 1, Biocytogen LLC
MGI:6860511
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ermntm1Bcgen/Ermntm1Bcgen involves: C57BL/6 MGI:6860524


Genotype
MGI:6860524
hm1
Allelic
Composition		 Ermntm1Bcgen/Ermntm1Bcgen
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ermntm1Bcgen mutation (0 available); any Ermn mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
impaired coordination ( J:297572 )
• on a rotarod at 1 year of age, but not earlier

nervous system
abnormal oligodendrocyte morphology ( J:297572 )
• impaired differentiation
demyelination ( J:297572 )
• in untreated mice and accelerated 3 weeks after cuprizone exposure
decreased nerve conduction velocity ( J:297572 )
• in untreated mice 1 year of age and accelerated after cuprizone exposure

cellular
abnormal oligodendrocyte morphology ( J:297572 )
• impaired differentiation




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory