Phenotypes associated with this allele

• Allele Symbol: Ermn^tm1Bcgen
• Allele Name: targeted mutation 1, Biocytogen LLC
• Allele ID: MGI:6860511
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ermn^tm1Bcgen/Ermn^tm1Bcgen	involves: C57BL/6	MGI:6860524

Genotype
MGI:6860524

hm1

• Allelic Composition: Ermn^tm1Bcgen/Ermn^tm1Bcgen
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

impaired coordination ( J:297572 )

• on a rotarod at 1 year of age, but not earlier

nervous system

abnormal oligodendrocyte morphology ( J:297572 )

• impaired differentiation

demyelination ( J:297572 )

• in untreated mice and accelerated 3 weeks after cuprizone exposure

decreased nerve conduction velocity ( J:297572 )

• in untreated mice 1 year of age and accelerated after cuprizone exposure