All Phenotypes Spata33<em1Osb> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Spata33^em1Osb
endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
MGI:6849782

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Spata33^em1Osb/Spata33^em1Osb	involves: C57BL/6NJcl * DBA/2NJcl	MGI:6849948

Allelic Composition	Spata33^em1Osb/Spata33^em1Osb
Genetic Background	involves: C57BL/6NJcl * DBA/2NJcl

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Spata33^em1Osb mutation (2 available); any Spata33 mutation (16 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

reproductive system phenotype ( J:309565 )

N	• sperm morphology is normal

• inflexible

abnormal sperm motility ( J:309565 )

• decrease in average path velocity, straight-line velocity, and curvilinear velocity

• however, the percentage of motile sperm is normal

reduced male fertility ( J:309565 )

• severely impaired fertility

impaired fertilization ( J:309565 )

• using mutant sperm in vitro despite removing the cumulus cells

• however, removing the cumulus cells and zona pellucida restores fertilization

cellular

• inflexible

abnormal sperm motility ( J:309565 )

• decrease in average path velocity, straight-line velocity, and curvilinear velocity

• however, the percentage of motile sperm is normal

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23