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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cenpvtm1c(EUCOMM)Hmgu
targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH
MGI:6838381
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Cenpvtm1c(EUCOMM)Hmgu/Cenpvtm1c(EUCOMM)Hmgu
Tg(Spo11-cre)1Rsw/0 		involves: C57BL/6N MGI:6838389
cn2
 		Cenpvtm1c(EUCOMM)Hmgu/Cenpvtm1c(EUCOMM)Hmgu
Tg(Ddx4-cre)1Dcas/0 		involves: C57BL/6N * FVB MGI:6838392
cn3
 		Cenpvtm1c(EUCOMM)Hmgu/Cenpvtm1c(EUCOMM)Hmgu
Tg(Stra8-icre)1Reb/0 		involves: C57BL/6N * FVB/NJ MGI:6838391


Genotype
MGI:6838389
cn1
Allelic
Composition		 Cenpvtm1c(EUCOMM)Hmgu/Cenpvtm1c(EUCOMM)Hmgu
Tg(Spo11-cre)1Rsw/0
Genetic
Background		 involves: C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cenpvtm1c(EUCOMM)Hmgu mutation (0 available); any Cenpv mutation (58 available)
Tg(Spo11-cre)1Rsw mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
impaired polar body extrusion ( J:314905 )
• decrease in polar body extrusion

cellular
impaired polar body extrusion ( J:314905 )
• decrease in polar body extrusion




Genotype
MGI:6838392
cn2
Allelic
Composition		 Cenpvtm1c(EUCOMM)Hmgu/Cenpvtm1c(EUCOMM)Hmgu
Tg(Ddx4-cre)1Dcas/0
Genetic
Background		 involves: C57BL/6N * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cenpvtm1c(EUCOMM)Hmgu mutation (0 available); any Cenpv mutation (58 available)
Tg(Ddx4-cre)1Dcas mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal female meiosis ( J:314905 )
• as in other mice carrying the conditional allele activated in oocytes by Tg(Stra8-icre)1Reb or Tg(Spo11-cre)1Rsw

cellular
abnormal female meiosis ( J:314905 )
• as in other mice carrying the conditional allele activated in oocytes by Tg(Stra8-icre)1Reb or Tg(Spo11-cre)1Rsw




Genotype
MGI:6838391
cn3
Allelic
Composition		 Cenpvtm1c(EUCOMM)Hmgu/Cenpvtm1c(EUCOMM)Hmgu
Tg(Stra8-icre)1Reb/0
Genetic
Background		 involves: C57BL/6N * FVB/NJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cenpvtm1c(EUCOMM)Hmgu mutation (0 available); any Cenpv mutation (58 available)
Tg(Stra8-icre)1Reb mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
impaired polar body extrusion ( J:314905 )
• decrease in polar body extrusion

cellular
impaired polar body extrusion ( J:314905 )
• decrease in polar body extrusion




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory