Phenotypes associated with this allele

• Allele Symbol: Ankrd31^em1Flor
• Allele Name: endonuclease-mediated mutation 1, Florian Guillou
• Allele ID: MGI:6831182
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ankrd31^em1Flor/Ankrd31^em1Flor	C57BL/6JCrl-Ankrd31^em1Flor	MGI:6831616

Genotype
MGI:6831616

hm1

• Allelic Composition: Ankrd31^em1Flor/Ankrd31^em1Flor
• Genetic Background: C57BL/6JCrl-Ankrd31^em1Flor

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reproductive system phenotype ( J:314966 )

♀N • female mice exhibit normal fertility

oligozoospermia ( J:314966 )

♂

abnormal sperm head morphology ( J:314966 )

♂

abnormal sperm nucleus morphology ( J:314966 )

♂ • increase in the number of aniline blue-positive cells with immature chromatin state and an unbalanced histone/protamine ratio

decreased sperm progressive motility ( J:314966 )

♂

asthenozoospermia ( J:314966 )

♂ • severe

abnormal seminiferous tubule epithelium morphology ( J:314966 )

♂ • complete degradation

small testis ( J:314966 )

♂

decreased testis weight ( J:314966 )

♂

abnormal male meiosis ( J:314966 )

♂ • unaligned chromosomes in metaphase

male infertility ( J:314966 )

♂

cellular

oligozoospermia ( J:314966 )

♂

abnormal sperm head morphology ( J:314966 )

♂

abnormal sperm nucleus morphology ( J:314966 )

♂ • increase in the number of aniline blue-positive cells with immature chromatin state and an unbalanced histone/protamine ratio

decreased sperm progressive motility ( J:314966 )

♂

asthenozoospermia ( J:314966 )

♂ • severe

endocrine/exocrine glands

abnormal seminiferous tubule epithelium morphology ( J:314966 )

♂ • complete degradation

small testis ( J:314966 )

♂

decreased testis weight ( J:314966 )

♂