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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Glipr2em1Blev
endonuclease-mediated mutation 1, Beth Levine
MGI:6828739
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Glipr2em1Blev/Glipr2em1Blev
Tg(CAG-EGFP/Map1lc3b)53Nmz/0 		involves: C57BL/6J * DBA/2 MGI:6828762


Genotype
MGI:6828762
cx1
Allelic
Composition		 Glipr2em1Blev/Glipr2em1Blev
Tg(CAG-EGFP/Map1lc3b)53Nmz/0
Genetic
Background		 involves: C57BL/6J * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Glipr2em1Blev mutation (0 available); any Glipr2 mutation (37 available)
Tg(CAG-EGFP/Map1lc3b)53Nmz mutation (5 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
enhanced autophagy ( J:312370 )
• increased autophagosomes in all tissues examined, including heart, liver, and skeletal muscle due to increased autophagic flux
• however, autophagosome maturation is normal

homeostasis/metabolism
enhanced autophagy ( J:312370 )
• increased autophagosomes in all tissues examined, including heart, liver, and skeletal muscle due to increased autophagic flux
• however, autophagosome maturation is normal




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory