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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tuba3aem2Smtb
endonuclease-mediated mutation 2, Shogo Matoba
MGI:6764564
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Tuba3aem2Smtb/Tuba3aem2Smtb
Tuba3bem2Smtb/Tuba3bem2Smtb 		C57BL/6NSlc-Tuba3aem2Smtb Tuba3bem2Smtb/Smtb MGI:6764585


Genotype
MGI:6764585
cx1
Allelic
Composition		 Tuba3aem2Smtb/Tuba3aem2Smtb
Tuba3bem2Smtb/Tuba3bem2Smtb
Genetic
Background		 C57BL/6NSlc-Tuba3aem2Smtb Tuba3bem2Smtb/Smtb
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tuba3aem2Smtb mutation (0 available); any Tuba3a mutation (20 available)
Tuba3bem2Smtb mutation (0 available); any Tuba3b mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:308859 )
N
• mice exhibit normal testis size
impaired sperm penetration of zona pellucida ( J:308859 )
• however, sperm can fertilize occytes with zona pellucida removed, and have normal morphology and motility




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory