Phenotypes associated with this allele

• Allele Symbol: Snx11^tm1Zhil
• Allele Name: targeted mutation 1, Zhiyuan Li
• Allele ID: MGI:6758755
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Snx11^tm1Zhil/Snx11^tm1Zhil	involves: 129S6/SvEvTac * C57BL/6J	MGI:6758756

Genotype
MGI:6758756

hm1

• Allelic Composition: Snx11^tm1Zhil/Snx11^tm1Zhil
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal thermosensation ( J:309511 )

• mice exhibit a stronger preference for warm temperatures compared with wild-type mice

decreased thermal nociceptive threshold ( J:309511 )

• in hot plate and water bath assays

integument

abnormal keratinocyte physiology ( J:309511 )

• keratinocytes exhibit a larger temperature-gated TRVP3 membrane current compared with wild-type keratinocyte