All Phenotypes Ndufa4l2<tm1.1Jlob> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ndufa4l2^tm1.1Jlob
targeted mutation 1.1, Jose Lopez-Barneo
MGI:6721091

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Ndufa4l2^tm1.1Jlob/Ndufa4l2^tm1.2Jlob Th^tm1(cre)Te/Th⁺	involves: 129S/Sv * 129X1/SvJ * C57BL/6NCrl * C57BL/6NTac	MGI:6724163

Allelic Composition	Ndufa4l2^tm1.1Jlob/Ndufa4l2^tm1.2Jlob Th^tm1(cre)Te/Th⁺
Genetic Background	involves: 129S/Sv * 129X1/SvJ * C57BL/6NCrl * C57BL/6NTac

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ndufa4l2^tm1.1Jlob mutation (0 available); any Ndufa4l2 mutation (9 available)
Ndufa4l2^tm1.2Jlob mutation (0 available); any Ndufa4l2 mutation (9 available)
Th^tm1(cre)Te mutation (1 available); any Th mutation (57 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

abnormal physiological response to hypoxia ( J:302384 )

• slightly higher responsiveness to hypoxia

• however, mice exhibit normal ventilatory responses to hypoxia and hypercapnia

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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